Moyamoya disease--diagnosis and treatment: indirect cerebral revascularization at the Sheba Medical Center

• Published in: The Israel Medical Association journal Vol. 7; no. 10; pp. 661 - 666
• Main Authors: Nissim, Ouzi, Bakon, Matti, Ben Zeev, Bruria, Goshen, Elinor, Knoller, Nachshon, Hadani, Moshe, Feldman, Zeev
• Format: Journal Article
• Language: English
• Published: Israel 01.10.2005
• Subjects: Adult; Cerebral Revascularization - adverse effects; Cerebral Revascularization - methods; Child; Female; Humans; Israel; Male; Moyamoya Disease - diagnosis; Moyamoya Disease - physiopathology; Moyamoya Disease - surgery; Israel
• ISSN: 1565-1088

Moyamoya disease is a cerebral vasculopathy characterized mainly by progressive narrowing of the major intracranial vessels. While more common and having a familial predilection in the Far East, it can also develop in association with some common hereditary diseases and can be acquired after environmental exposure. In the young its manifestations are the result of cerebral ischemia. Adults usually suffer from repeated incidents of intracerebral hemorrhage. Surgical revascularization of ischemic cerebral territories plays a major role in their treatment. We review the literature and present our series of three adult and five pediatric patients; these patients were diagnosed at our institution and treated with indirect revascularization techniques.