Relationship between metabolic syndrome and erectile dysfunction

• Published in: Asian journal of andrology Vol. 6; no. 4; pp. 355 - 358
• Main Authors: Gündüz, M I, Gümüs, B H, Sekuri, C
• Format: Journal Article
• Language: English
• Published: China 01.12.2004
• Subjects: Adult; Aged; Body Mass Index; Coronary Artery Disease - complications; Coronary Artery Disease - epidemiology; Erectile Dysfunction - complications; Erectile Dysfunction - epidemiology; Humans; Hypercholesterolemia - complications; Hypercholesterolemia - epidemiology; Hyperlipidemias - complications; Hyperlipidemias - epidemiology; Male; Metabolic Syndrome - complications; Metabolic Syndrome - epidemiology; Middle Aged; Risk Factors
• ISSN: 1008-682X; 1745-7262

To determine the relationship between metabolic syndrome (MS) and erectile dysfunction (ED) and to see which risk factors correlated the best with ED. Seventy-nine cardiology clinic outpatients with coronary artery disease (CAD) and lipid metabolism disorder were recruited. They were categorized as having MS, hypertension (blood pressure greater than 130/85 mmHg) and dyslipidemia. ED was classified based on International Index of Erectile Function scores. Patients were grouped into quartiles based on body mass index (BMI). Chi-square, Pearson's correlation and regression tests were used for statistical analysis. The mean age of the patients was 56.6 years. ED was diagnosed in 59 (74.7 %) of the 79 patients. In the 38 patients with MS, all had ED. ED was not significantly correlated with cholesterol levels (P>0.05), but was found often in patients who had both hypercholesterolemia and HT (P<0.01). Nineteen (76 %) of the 25 patients who had dyslipidemia had ED. However, ED was not significantly correlated with dyslipidemia (P >0.05). Twenty-two of the 23 patients who had BMI greater than 30 had ED, which was significantly more prevalent than that in those who had normal BMI (P<0.01). ED was seen in 38 of 53 smoker patients. Although ED was more prevalent in cigarette smokers, it was not significantly different from non-smokers (P>0.5). ED is present in a high percentage of patients with MS. Among multiple risk factors for ED, MS correlates the most highly. The next most important risk group is the patients with hypertension +hypercholestrolemia and obesity (BMI 30).