Branch retinal artery occlusions as the presenting feature of primary central nervous system vasculitis

A 39-year-old woman presented with multiple branch retinal artery occlusions almost three years before developing a mass lesion containing calcium in the left frontal lobe. Brain biopsy revealed a small vessel vasculitis and ischemic necrosis of brain with dystrophic calcification. We believe this t...

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Bibliographic Details
Published inClinical and experimental rheumatology Vol. 22; no. 6 Suppl 36; p. S70
Main Authors Susac, J O, Calabrese, L H, Baylin, E, Prayson, R A, Medeiros, N E, Hull, R P, Tucker, J P
Format Journal Article
LanguageEnglish
Published Italy 2004
Subjects
Adult
Brain - blood supply
Brain - diagnostic imaging
Brain - pathology
Calcinosis - diagnostic imaging
Calcinosis - pathology
Cyclophosphamide - therapeutic use
Diagnostic Techniques, Ophthalmological
Female
Humans
Immunosuppressive Agents - therapeutic use
Mycophenolic Acid - analogs & derivatives
Mycophenolic Acid - therapeutic use
Prednisone - therapeutic use
Retinal Artery Occlusion - drug therapy
Retinal Artery Occlusion - etiology
Retinal Artery Occlusion - pathology
Tomography, X-Ray Computed
Treatment Outcome
Vasculitis, Central Nervous System - complications
Vasculitis, Central Nervous System - drug therapy
Vasculitis, Central Nervous System - pathology
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Summary:A 39-year-old woman presented with multiple branch retinal artery occlusions almost three years before developing a mass lesion containing calcium in the left frontal lobe. Brain biopsy revealed a small vessel vasculitis and ischemic necrosis of brain with dystrophic calcification. We believe this to be the first case of primary CNS vasculitis with branch retinal artery occlusions and brain calcification.
ISSN:0392-856X