The placenta and protein metabolism; transfer studies using carbon 14-labeled proteins in dogs

• Published in: The Journal of experimental medicine Vol. 101; no. 6; pp. 617 - 626
• Main Authors: WHIPPLE, G H, HILL, Jr, R B, TERRY, R, LUCAS, F V, YUILE, C L
• Format: Journal Article
• Language: English
• Published: United States 01.06.1955
• Subjects: Amino Acids; Animals; Biological Transport; Blood Proteins; Carbon; Carbon Radioisotopes; Dogs; Female; Fetal Development; Fetus; Injections, Intravenous; Liver; Lysine; Old Medline; Placenta - physiology; Pregnancy; Rabbits; CARBON/radioactive; PLACENTA/physiology; BLOOD PROTEINS

Plasma proteins tagged in vivo by feeding D-L-lysine-epsilon-C(14) to donor dogs have been administered to pregnant dogs by both oral and intravenous routes. A relatively small percentage of the C(14) activity originally incorporated in these proteins is found to pass from mother to fetus after intr...