5-Amidinoindoles as dual inhibitors of coagulation factors IXa and Xa
Structural features of a 5-amidinoindole inhibitor of factor Xa, which displayed modest inhibition of factor IXa were varied to increase potency and improve selectivity for factor IXa.
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Published in | Bioorganic & medicinal chemistry letters Vol. 14; no. 21; pp. 5269 - 5273 |
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Main Authors | , , , , , , , , , |
Format | Journal Article |
Language | English |
Published |
England
01.11.2004
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Subjects | |
Online Access | Get full text |
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