Reduced deformability of erythrocytes as feature of congenital dyserythropoietic anaemia type II (HEMPAS)

• Published in: Clinical hemorheology and microcirculation Vol. 21; no. 3-4; pp. 425 - 430
• Main Authors: Izzo, P, Spagnuolo, A, Manicone, A, Nazzaro, P, Lauta, V M
• Format: Journal Article
• Language: English
• Published: Netherlands 1999
• Subjects: Adolescent; Anemia, Dyserythropoietic, Congenital - blood; Erythrocyte Deformability; Erythrocyte Indices; Erythrocytes - metabolism; Erythrocytes - pathology; Erythrocytes - ultrastructure; Female; Hemoglobins - metabolism; Humans; Lasers; Male; Middle Aged; Optical Rotation

In this study we report results regarding erythrocytes deformability in congenital dyserythropoietic anemia type II (HEMPAS) by the use of LORCA (Laser-assisted Optical Rotational Cell Analyzer). The reduced erythrocytes deformability observed in seven case of CDA II is caused by changes in the stru...