Increased expression of sialyl Lewis(x) antigen in penetrating growth type A early gastric cancer

• Published in: Journal of experimental & clinical cancer research Vol. 21; no. 3; p. 363
• Main Authors: Nakagoe, T, Fukushima, K, Sawai, T, Tsuji, T, Jibiki, M, Nanashima, A, Tanaka, K, Yamaguchi, H, Yasutake, T, Ayabe, H, Ishikawa, H
• Format: Journal Article
• Language: English
• Published: England 01.09.2002
• Subjects: Adenocarcinoma - metabolism; Adenocarcinoma - secondary; Antibodies, Monoclonal - immunology; Biomarkers, Tumor; Cell Differentiation; Female; Gastrectomy; Gastric Mucosa - metabolism; Gastric Mucosa - pathology; Humans; Immunoenzyme Techniques; Lewis X Antigen - metabolism; Lymphatic Metastasis; Male; Middle Aged; Neoplasm Invasiveness; Neoplasm Staging; Prognosis; Stomach Neoplasms - metabolism; Stomach Neoplasms - pathology; Survival Rate

Early gastric cancer can be divided morphologically into two categories, penetrating growth type-A (Pen-A type) and other growth types (non-Pen-A types). Sialyl Lewis(x) antigen has been demonstrated to play an important role in tumor metastasis by serving as a functional ligand in the cell adhesion...