Nucleic acid components and their analogues: A novel and efficient method for the synthesis of a new class of bipyridyl and biheterocyclic-nitrogen thioglycosides from pyridine-2(1H)-thiones

• Published in: Nucleosides, nucleotides & nucleic acids Vol. 21; no. 6-7; pp. 477 - 493
• Main Authors: Elgemeie, GH, El-Enany, MM, Ismail, MM, Ahmed, EK
• Format: Journal Article
• Language: English
• Published: PHILADELPHIA Taylor & Francis 01.06.2002
• Subjects: 2,2'-Dipyridyl - chemical synthesis; 2,2'-Dipyridyl - chemistry; Biochemistry & Molecular Biology; Cycloparaffins - chemistry; Galactose - chemistry; Glucose - chemistry; Heterocyclic Compounds - chemical synthesis; Heterocyclic Compounds - chemistry; Life Sciences & Biomedicine; Magnetic Resonance Spectroscopy; Nitriles - chemistry; Nitrogen - chemistry; Science & Technology; Thioglycosides - chemical synthesis; Thiones - chemistry; biheterocyclic thioglycosides; pyridine-2(1H)-thiones; NUCLEOSIDES; pyridine thioglycosides; coupling reactions

A novel synthesis of a new class of bipyridyl and biheterocyclic-nitrogen thioglycosides utilizing the reactions of heterocyclic substituted pyridine-2(1H)-thiones and alpha-bromoglucose or alpha-bromogalactose tetraacetate as starting components is described.