The soluble IL-6 receptors: serum levels and biological function

IL-6 exerts its biological activities through interaction with specific receptors expressed on the surface of target cells. IL-6 binds first to a low-affinity (10(-9) M) subunit, a 80 kDa glycoprotein also called gp80 or IL-6R alpha. The IL-6/IL-6R alpha complex recruits the signal-transducing b sub...

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Bibliographic Details
Published inCellular and molecular biology (Noisy-le-Grand, France) Vol. 47; no. 4; p. 583
Main Author Montero-Julian, F A
Format Journal Article
LanguageEnglish
Published France 01.06.2001
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