Energy metabolism in Leishmania

• Published in: Journal of bioenergetics and biomembranes Vol. 26; no. 2; p. 147
• Main Author: Blum, J J
• Format: Journal Article
• Language: English
• Published: United States 01.04.1994
• Subjects: Alanine - metabolism; Animals; Arginine - metabolism; Energy Metabolism; Fatty Acids - metabolism; Glucose - metabolism; Glyoxylates - metabolism; Leishmania - metabolism; Leucine - metabolism; Mannans - metabolism; Oxidation-Reduction

Alanine plays a key role in the response of promastigotes to osmotic stress and to hypoxia. It is rapidly released in response to hypo-osmolality, is consumed from its large intracellular pool under iso-osmotic conditions even in the presence of glucose, and is synthesized under hyperosmotic conditi...