Modified western blot with recombinant antigens for serological differentiation between HTLV-I and HTLV-II

• Published in: The New microbiologica Vol. 17; no. 3; p. 177
• Main Authors: Chironna, M, Quarto, M, Germinario, C, Fontana, A
• Format: Journal Article
• Language: English
• Published: Italy 01.07.1994
• Subjects: Blotting, Western - methods; Deltaretrovirus Antibodies - blood; Deltaretrovirus Antigens; HTLV-I Infections - classification; HTLV-I Infections - diagnosis; HTLV-I Infections - epidemiology; HTLV-I Infections - immunology; HTLV-II Infections - classification; HTLV-II Infections - diagnosis; HTLV-II Infections - epidemiology; HTLV-II Infections - immunology; Humans; Italy - epidemiology; Recombinant Proteins; Italy

Some epidemiological and clinical features of HTLV-I and HTLV-II infections remain unclear due to the inability to confirm and distinguish between the two retroviruses. Since HTLV-I and HTLV-II have a high degree of genomic and aminoacid sequence homology, serologic crossreactions are frequent, maki...