Characterization of functional neurotensin receptors on human lymphocytes

• Published in: Surgery Vol. 116; no. 2; p. 134
• Main Authors: Evers, B M, Bold, R J, Ehrenfried, J A, Li, J, Townsend, Jr, C M, Klimpel, G R
• Format: Journal Article
• Language: English
• Published: United States 01.08.1994
• Subjects: Blotting, Northern; Cell Line; Humans; Lymphocyte Activation - drug effects; Lymphocytes - chemistry; Neurotensin - metabolism; Neurotensin - pharmacology; Receptors, Neurotensin - analysis; Receptors, Neurotensin - genetics; Receptors, Neurotensin - physiology; Ribonucleases - pharmacology

Neurotensin, a tridecapeptide, regulates gut motility, secretion, and mucosal growth; an immunomodulatory role for neurotensin has been postulated but not clearly defined. The purpose of this study was to determine whether neurotensin receptors (NTR) are present on peripheral blood lymphocytes (PBLs...