Intratumoral administration of 5-[123I]iodo-2'-deoxyuridine in a patient with a brain tumor

• Published in: The Journal of nuclear medicine (1978) Vol. 37; no. 4 Suppl; pp. 19S - 22S
• Main Authors: Kassis, A I, Tumeh, S S, Wen, P Y, Baranowska-Kortylewicz, J, Van den Abbeele, A D, Zimmerman, R E, Carvalho, P A, Garada, B M, DeSisto, W C, Bailey, N O, Castronovo, Jr, F P, Mariani, G, Black, P M, Adelstein, S J
• Format: Journal Article
• Language: English
• Published: United States 01.04.1996
• Subjects: Adult; Astrocytoma - diagnostic imaging; Astrocytoma - radiotherapy; Brain Neoplasms - diagnostic imaging; Brain Neoplasms - radiotherapy; Female; Humans; Idoxuridine - administration & dosage; Idoxuridine - pharmacokinetics; Idoxuridine - therapeutic use; Injections, Intralesional; Iodine Radioisotopes - administration & dosage; Iodine Radioisotopes - pharmacokinetics; Iodine Radioisotopes - therapeutic use; Radionuclide Imaging; Radiotherapy Dosage; Tissue Distribution

We have initiated a study in which patients suspected of having primary gliomas are given a single intracerebral injection of the thymidine analog 5-[123I]iodo-2'-deoxyuridine ([123I]IUdR). The purpose of the study is to determine the biodistribution of the radiopharmaceutical and to calculate...