Enzymes utilizing glutamine as an amide donor

• Published in: Advances in enzymology and related subjects Vol. 72; p. 87
• Main Authors: Zalkin, H, Smith, J L
• Format: Journal Article
• Language: English
• Published: United States 1998
• Subjects: Allosteric Regulation; Amides - metabolism; Carbon-Nitrogen Ligases - metabolism; Gene Expression Regulation, Enzymologic; Glutamine - metabolism; Humans; Models, Molecular; Transferases - metabolism

Amide nitrogen from glutamine is a major source of nitrogen atoms incorporated biosynthetically into other amino acids, purine and pyrimidine bases, amino-sugars, and coenzymes. A family comprised of at least sixteen amidotransferases are known to catalyze amide nitrogen transfer from glutamine to t...