Novel costimulators in the immune gene therapy of cancer

• Published in: Cancer gene therapy Vol. 3; no. 3; p. 202
• Main Authors: Galea-Lauri, J, Farzaneh, F, Gäken, J
• Format: Journal Article
• Language: English
• Published: England 01.05.1996
• Subjects: Abatacept; Animals; Antigens, CD; Antigens, Differentiation - immunology; Antigens, Neoplasm - immunology; Antigens, Surface - immunology; B7-1 Antigen - immunology; Biomarkers, Tumor; CD28 Antigens - immunology; CTLA-4 Antigen; Cytotoxicity, Immunologic; Genetic Therapy - methods; Humans; Immunocompromised Host; Immunoconjugates; Immunotherapy - methods; Killer Cells, Natural - immunology; Models, Immunological; Neoplasms - immunology; Neoplasms - therapy; Receptors, Antigen, T-Cell - immunology; Signal Transduction; T-Lymphocytes - immunology

One of the major goals of cancer immunotherapy is the induction of tumour-specific T-lymphocyte responses that will be effective in the rejection of established tumours. The prospects for such therapy rely on the identification of tumour antigens, and although there is persuasive evidence for the pr...