In vivo characterization of downfield peaks at 9.4 T: T2 relaxation times, quantification, pH estimation, and assignments

• Published in: Magnetic resonance in medicine Vol. 85; no. 2; pp. 587 - 600
• Main Authors: Borbath, Tamas, Murali‐Manohar, Saipavitra, Wright, Andrew Martin, Henning, Anke
• Format: Journal Article
• Language: English
• Published: Hoboken Wiley Subscription Services, Inc 01.02.2021
• Subjects: Adenosine triphosphate; Antifungal agents; downfield; exchange rates; Foreign exchange rates; Imidazole; Mathematical analysis; Metabolites; MR spectroscopy; N-Acetylaspartylglutamic acid; pH effects; Protons; quantification; Spectra; T2 relaxation time; ultra‐high field; Urea

Purpose Relaxation times are a valuable asset when determining spectral assignments. In this study, apparent T2 relaxation times (T2app) of downfield peaks are reported in the human brain at 9.4 T and are used to guide spectral assignments of some downfield metabolite peaks. Methods Echo time series...