VERIFY (VERification of Instantaneous Wave-Free Ratio and Fractional Flow Reserve for the Assessment of Coronary Artery Stenosis Severity in EverydaY Practice): A Multicenter Study in Consecutive Patients

• Published in: Journal of the American College of Cardiology Vol. 61; no. 13; pp. 1421 - 1427
• Main Authors: BERRY, Colin, VAN'T VEER, Marcel, DE BRUYNE, Bernard, PIJLS, Nico H. J, OLDROYD, Keith G, WITT, Nils, KALA, Petr, BOCEK, Otakar, PYXARAS, Stylianos A, MCCLURE, John D, FEARON, William F, BARBATO, Emanuele, TONINO, Pim A. L
• Format: Journal Article
• Language: English
• Published: New York, NY Elsevier 02.04.2013
• Subjects: Adenosine - administration & dosage; Aged; Biological and medical sciences; Blood and lymphatic vessels; Cardiology. Vascular system; Coronary Angiography; Coronary Stenosis - diagnosis; Coronary Stenosis - pathology; Coronary Stenosis - physiopathology; Diseases of the peripheral vessels. Diseases of the vena cava. Miscellaneous; Female; Fractional Flow Reserve, Myocardial - physiology; Humans; Hyperemia - physiopathology; Infusions, Intravenous; Male; Medical sciences; Medicin och hälsovetenskap; Middle Aged; Myocardial Contraction - physiology; ROC Curve; Severity of Illness Index; Vasodilator Agents - administration & dosage; Human; Reserve; Multicenter study; Coronary artery; Cardiovascular disease; Patient; Verification; Artery stenosis; Arterial disease; Vascular disease; Wave; Professional practice; Ratio; Circulatory system; Cardiology

This study sought to compare fractional flow reserve (FFR) with the instantaneous wave-free ratio (iFR) in patients with coronary artery disease and also to determine whether the iFR is independent of hyperemia. FFR is a validated index of coronary stenosis severity. FFR-guided percutaneous coronary...