Plasma-derived exosomal immunoglobulins IGHV4-4 and IGLV1-40 as new non-small cell lung cancer biomarkers

• Published in: American journal of cancer research Vol. 13; no. 5; pp. 1923 - 1937
• Main Authors: Yang, Peng, Zhang, Yang, Zhang, Ruping, Wang, Yun, Zhu, Shengjin, Peng, Xin, Zeng, Yimin, Yang, Bing, Pan, Meijun, Gong, Jie, Ba, Hongping
• Format: Journal Article
• Language: English
• Published: United States e-Century Publishing Corporation 01.01.2023
• Subjects: Original; immunoglobulin lambda variable 1-40; Exosome; diagnostic biomarkers; immunoglobulin heavy variable 4-4; non-small-cell lung cancer

Exosomal proteins represent valuable research directions in the liquid biopsy of lung cancer (LC). Immunoglobulin subtypes, immunoglobulin molecules with different domains in variable regions, are products of B cell responses to different tumor antigens and are associated with tumor incidence and de...