Cancer stem cells: a major culprit of intra-tumor heterogeneity

• Published in: American journal of cancer research Vol. 11; no. 12; pp. 5782 - 5811
• Main Authors: Naz, Faiza, Shi, Mengran, Sajid, Salvia, Yang, Zhao, Yu, Changyuan
• Format: Journal Article
• Language: English
• Published: United States e-Century Publishing Corporation 01.01.2021
• Subjects: Review; Cancer stem cells; metastasis; therapy resistance; tumor heterogeneity

Cancer is recognized as a preeminent factor of the world's mortality. Although various modalities have been designed to cure this life-threatening ailment, a significant impediment in the effective output of cancer treatment is heterogeneity. Cancer is characterized as a heterogeneous health di...