Exosomal transfer of miR-429 confers chemoresistance in epithelial ovarian cancer

• Published in: American journal of cancer research Vol. 11; no. 5; pp. 2124 - 2141
• Main Authors: Li, Taoqiong, Lin, Li, Liu, Qin, Gao, Wujiang, Chen, Lu, Sha, Chunli, Chen, Qi, Xu, Wenlin, Li, Yuefeng, Zhu, Xiaolan
• Format: Journal Article
• Language: English
• Published: United States e-Century Publishing Corporation 01.01.2021
• Subjects: Original; EOC; miR-429; NF-κB; chemoresistance; Exosome

The development of multidrug resistance during chemotherapy is the main obstacle for epithelial ovarian cancer (EOC) treatment. Exosomal transfer of carcinogenic microRNAs (miRNAs) might strengthen chemoresistance in recipient cells. Here, we identified through microarray analysis higher miR-429 exp...