A possible neural mechanism for photosensitivity in chronic pain

• Published in: Pain (Amsterdam) Vol. 157; no. 4; pp. 868 - 878
• Main Authors: Martenson, Melissa E, Halawa, Omar I, Tonsfeldt, Karen J, Maxwell, Charlene A, Hammack, Nora, Mist, Scott D, Pennesi, Mark E, Bennett, Robert M, Mauer, Kim M, Jones, Kim D, Heinricher, Mary M
• Format: Journal Article
• Language: English
• Published: United States 01.04.2016
• Subjects: Action Potentials - physiology; Adult; Aged; Brain Stem - physiopathology; Chronic Pain - physiopathology; Female; Humans; Hyperalgesia - physiopathology; Light; Medulla Oblongata - physiopathology; Middle Aged; Neurons - physiology; Pain Measurement - methods

Patients with functional pain disorders often complain of generalized sensory hypersensitivity, finding sounds, smells, or even everyday light aversive. The neural basis for this aversion is unknown, but it cannot be attributed to a general increase in cortical sensory processing. Here, we quantifie...