Lack of Improvement in Renal Allograft Survival Despite a Marked Decrease in Acute Rejection Rates Over the Most Recent Era

• Published in: American journal of transplantation Vol. 4; no. 3; pp. 378 - 383
• Main Authors: Meier‐Kriesche, Herwig‐Ulf, Schold, Jesse D., Srinivas, Titte R., Kaplan, Bruce
• Format: Journal Article
• Language: English
• Published: 9600 Garsington Road , Oxford , OX4 2DQ , UK Munksgaard International Publishers 01.03.2004
• Subjects: Acute rejection; era effect; Graft Rejection - mortality; Graft Survival; Humans; Kidney - physiology; Kidney - surgery; kidney transplantation; Kidney Transplantation - immunology; Kidney Transplantation - mortality; Tissue Donors

Acute rejection is known to have a strong impact on graft survival. Many studies suggest that very low acute rejection rates can be achieved with current immunosuppressive protocols. We wanted to investigate how acute rejection rates have evolved on a national level in the U.S. and how this has impa...