Association between lung cancer risk and single nucleotide polymorphisms in the first intron and codon 178 of the DNA repair gene, O6‐alkylguanine–DNA alkyltransferase - Crosbie, Philip A.J.; McGown, Gail; Thorncroft, Mary R.; O'Donnell, Paul N.S.; Barber, Philip V.; Lewis, Sarah J.; Harrison, Kathryn L.; Agius, Raymond M.; Santibáñez‐Koref, Mauro F.; Margison, Geoffrey P.; Povey, Andrew C. (International journal of cancer, 2008)
Keywords: Adenocarcinoma - enzymology; Adenocarcinoma - etiology; Aged; AGT; Biological and medical sciences; Carcinoma, Small Cell - enzymology; Carcinoma, Small Cell - etiology; Carcinoma, Squamous Cell - enzymology; Carcinoma, Squamous Cell - etiology; Case-Control Studies; Codon - genetics; DNA alkylation; DNA Repair - genetics; Female; Genetic Predisposition to Disease; Genotype; Humans; Introns - genetics; lung cancer; Lung Neoplasms - enzymology; Lung Neoplasms - etiology; Male; Medical sciences; MGMT; Middle Aged; O-Methylguanine-DNA Methyltransferase - genetics; Pneumology; Polymorphism, Single Nucleotide - genetics; polymorphisms; Risk Factors; Smoking - adverse effects; tobacco smoke; Tumors; Tumors of the respiratory system and mediastinum; United Kingdom; Europe; Genetic variability; Lung cancer; Tobacco smoking; Epidemiology; DNA repair; Alkylation; Repair gene; Cancerology; Codon; Genetics; Bronchus disease; Human; Lung disease; tobacco smoke; Enzyme; Respiratory disease; MGMT; Transferases; Genotype; DNA alkylation; Malignant tumor; polymorphisms; AGT; Methylated-DNA-protein-cysteine S-methyltransferase; Tobacco; Methyltransferases; Intron; DNA; Risk factor; Single nucleotide polymorphism; Cancer