Model‐based frequency‐and‐phase correction of 1H MRS data with 2D linear‐combination modeling

• Published in: Magnetic resonance in medicine Vol. 92; no. 5; pp. 2222 - 2236
• Main Authors: Simicic, Dunja, Zöllner, Helge J., Davies‐Jenkins, Christopher W., Hupfeld, Kathleen E., Edden, Richard A. E., Oeltzschner, Georg
• Format: Journal Article
• Language: English
• Published: Hoboken Wiley Subscription Services, Inc 01.11.2024
• Subjects: 2D linear‐combination model; Amplitudes; Datasets; Errors; Estimates; Estimation; frequency‐and‐phase correction; Lower bounds; magnetic resonance spectroscopy; Metabolites; Modelling; Phase variations; Registration; spectral registration; Synthetic data

Purpose Retrospective frequency‐and‐phase correction (FPC) methods attempt to remove frequency‐and‐phase variations between transients to improve the quality of the averaged MR spectrum. However, traditional FPC methods like spectral registration struggle at low SNR. Here, we propose a method that d...