HLA-DRB10401 and HLA-DRB10408 Are Strongly Associated with the Development of Antibodies against Interferon-β Therapy in Multiple Sclerosis - HOFFMANN, Steve; CEPOK, Sabine; HEMMER, Bernhard; GRUMMEL, Verena; LEHMANN-HORN, Klaus; HACKERMUELLER, Jörg; STADLER, Peter F; HARTUNG, Hans-Peter; BERTHELE, Achim; DEISENHAMMER, Florian; WASMUTH, Ralf (American journal of human genetics, 2008)
Keywords: Adolescent; Adult; Aged; Alleles; Biological and medical sciences; Computational Biology - methods; Female; Fundamental and applied biological sciences. Psychology; Gene Expression Regulation; General aspects. Genetic counseling; Genetics of eukaryotes. Biological and molecular evolution; HLA Antigens - chemistry; HLA-DR Antigens - metabolism; HLA-DRB1 Chains; Humans; Interferon-beta - immunology; Interferon-beta - metabolism; Male; Medical genetics; Medical sciences; Middle Aged; Molecular and cellular biology; Multiple Sclerosis - genetics; Multiple Sclerosis - immunology; Multiple Sclerosis - metabolism; Multiple sclerosis and variants. Guillain barré syndrome and other inflammatory polyneuropathies. Leukoencephalitis; Neurology; Human; HLA-System; Therapy; Nervous system diseases; Multiple sclerosis; Antibody; Major histocompatibility system; Cytokine; Inflammatory disease; Association; Treatment; Central nervous system disease; Beta interferon; Development; Genetics; Class I histocompatibility antigen