Synovial fluid-derived exosomal lncRNA PCGEM1 as biomarker for the different stages of osteoarthritis

• Published in: International orthopaedics Vol. 42; no. 12; pp. 2865 - 2872
• Main Authors: Zhao, Ye, Xu, Juan
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer Berlin Heidelberg 01.12.2018
• Subjects: Biomarkers - metabolism; Exosomes; Humans; Medicine; Medicine & Public Health; Original Paper; Orthopedics; Osteoarthritis - diagnosis; Osteoarthritis - genetics; Osteoarthritis - metabolism; RNA, Long Noncoding - genetics; RNA, Long Noncoding - metabolism; ROC Curve; Synovial Fluid - metabolism; Exosomes; Osteoarthritis; lncRNA

Objects The purpose of this study is to investigate the role of exosomal lncRNAs from plasma and from synovial fluid in patients with osteoarthritis (OA) and to determine their diagnostic value in distinguishing the early stage of OA from progressive stage of OA. Methods Participants were divided in...