Rapidly shifting immunologic landscape and severity of SARS-CoV-2 in the Omicron era in South Africa

• Published in: medRxiv : the preprint server for health sciences
• Main Authors: Sun, Kaiyuan, Tempia, Stefano, Kleynhans, Jackie, von Gottberg, Anne, McMorrow, Meredith L, Wolter, Nicole, Bhiman, Jinal N, Moyes, Jocelyn, Carrim, Maimuna, Martinson, Neil A, Kahn, Kathleen, Lebina, Limakatso, du Toit, Jacques D, Mkhencele, Thulisa, Viboud, Cécile, Cohen, Cheryl
• Format: Journal Article
• Language: English
• Published: United States 22.08.2022

South Africa was among the first countries to detect the SARS-CoV-2 Omicron variant. Propelled by increased transmissibility and immune escape properties, Omicron displaced other globally circulating variants within 3 months of its emergence. Due to limited testing, Omicron's attenuated clinica...