Fluorescent probes based on an oxonium-coumarin scaffold for the detection of SO2 derivatives

In this work, a pair of fluorescent probes CPO were designed for the detection of SO2 derivatives based on the FRET principle. The acceptor part of the CPO probes is made of oxonium and the donor part is coumarin derivatives. Probe CPO1 has stable chemical properties and relatively outstanding optic...

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Published inNew journal of chemistry Vol. 46; no. 37; pp. 18090 - 18099
Main Authors Feng, Jing, Shen, Weiliang, Mou, Yi, Zhou, Zhiping, Li, Yuxiu, Han, Wei, Li, Bingdong
Format Journal Article
LanguageEnglish
Published CAMBRIDGE Royal Soc Chemistry 26.09.2022
Royal Society of Chemistry
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Abstract In this work, a pair of fluorescent probes CPO were designed for the detection of SO2 derivatives based on the FRET principle. The acceptor part of the CPO probes is made of oxonium and the donor part is coumarin derivatives. Probe CPO1 has stable chemical properties and relatively outstanding optical properties, with ultra-fast response time (<30 s), excellent specificity ability, a 137 nm emission window gap, and mitochondrial targeting capability; it was used for cell experiments and prepared as fluorescent strips for the measurement of Na2SO3 concentrations in aqueous solutions. Probe CPO2 exhibits obvious variation in the fluorescence ratio in different solvents. Owing to the weak fluorescence of CPO2, compound CPO2 was not utilized for further experiments.
AbstractList In this work, a pair of fluorescent probes CPO were designed for the detection of SO2 derivatives based on the FRET principle. The acceptor part of the CPO probes is made of oxonium and the donor part is coumarin derivatives. Probe CPO1 has stable chemical properties and relatively outstanding optical properties, with ultra-fast response time (<30 s), excellent specificity ability, a 137 nm emission window gap, and mitochondrial targeting capability; it was used for cell experiments and prepared as fluorescent strips for the measurement of Na2SO3 concentrations in aqueous solutions. Probe CPO2 exhibits obvious variation in the fluorescence ratio in different solvents. Owing to the weak fluorescence of CPO2, compound CPO2 was not utilized for further experiments.
Author Han, Wei
Li, Yuxiu
Shen, Weiliang
Zhou, Zhiping
Li, Bingdong
Feng, Jing
Mou, Yi
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Keywords VISUALIZATION
PLATFORM
CELLS
PEROXYNITRITE
SULFUR-DIOXIDE
MITOCHONDRIA
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WATER
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Snippet In this work, a pair of fluorescent probes CPO were designed for the detection of SO2 derivatives based on the FRET principle. The acceptor part of the CPO...
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SubjectTerms Aqueous solutions
Chemical properties
Chemistry
Chemistry, Multidisciplinary
Coumarin
Fluorescent indicators
Optical properties
Physical Sciences
Response time
Science & Technology
Sodium sulfite
Title Fluorescent probes based on an oxonium-coumarin scaffold for the detection of SO2 derivatives
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