Cystatin C and Long-Term Mortality Among Subjects With Normal Creatinine-Based Estimated Glomerular Filtration Rates: NHANES III (Third National Health and Nutrition Examination Survey)

• Published in: Journal of the American College of Cardiology Vol. 56; no. 23; pp. 1930 - 1936
• Main Authors: WU, Cho-Kai, LIN, Jou-Wei, CAFFREY, James L, CHANG, Man-Huei, HWANG, Juey-Jen, LIN, Yu-Sheng
• Format: Journal Article
• Language: English
• Published: New York, NY Elsevier 30.11.2010; Elsevier Limited
• Subjects: Adolescent; Adult; Age; Biological and medical sciences; Cancer; Cardiology; Cardiology. Vascular system; Cardiovascular disease; Cardiovascular Diseases - blood; Cardiovascular Diseases - etiology; Cardiovascular Diseases - mortality; Child; Cholesterol; Confidence intervals; Creatinine - blood; Cystatin C - blood; Diabetes; Female; Follow-Up Studies; Glomerular Filtration Rate; Glucose; Health Surveys; Humans; Hypertension; Kidney diseases; Kidney Diseases - blood; Kidney Diseases - mortality; Kidney Diseases - physiopathology; Lipoproteins; Male; Medical sciences; Middle Aged; Mortality; Multivariate analysis; Nutrition research; Nutrition Surveys; Population; Proteins; Retrospective Studies; Risk Factors; Smoking; Studies; Survival Rate - trends; Time Factors; United States - epidemiology; Variables; Variance analysis; Young Adult; United States; United States > US; Creatinine; Human; Glomerular filtration; Prognosis; Nutrition; Health; Mortality; Rate; Normal; Long term; Feeding; Survey; Circulatory system; Cardiology

The objective was to test the association of cystatin C (Cys-C) with long-term mortality risk in the subjects with normal creatinine-based estimated glomerular filtration rates (eGFR). Cys-C has been proposed as a sensitive indicator of renal dysfunction that is associated with cardiovascular events...