A novel microporous biomaterial vaccine platform for long-lasting antibody mediated immunity against viral infection

• Published in: bioRxiv : the preprint server for biology
• Main Authors: Mayer, Daniel P, Neslon, Mariah E, Andriyanova, Daria, Antao, Olivia Q, Chen, Jennifer S, Scumpia, Philip O, Weaver, Westbrook M, Deshayes, Stephanie, Weinstein, Jason S
• Format: Journal Article
• Language: English
• Published: United States 31.01.2024

Current antigen delivery platforms, such as alum and nanoparticles, are not readily tunable, thus may not generate optimal adaptive immune responses. We created an antigen delivery platform by loading lyophilized Microporous Annealed Particle (MAP) with aqueous solution containing target antigens. U...