Superior virological efficacy of ritonavir-boosted protease inhibitor regimens compared to single protease inhibitor therapy

• Published in: European journal of medical research Vol. 8; no. 2; p. 56
• Main Authors: Lichterfeld, M, Wöhrmann, A, Schmeisser, N, Fätkenheuer, G, Salzberger, B, Wyen, C, Schmitz, K, Sauerbruch, T, Rockstroh, J K
• Format: Journal Article
• Language: English
• Published: England 21.02.2003
• Subjects: Adult; Aged; Anti-HIV Agents - administration & dosage; Anti-HIV Agents - therapeutic use; Drug Therapy, Combination; Female; HIV - drug effects; HIV Infections - drug therapy; HIV Infections - virology; HIV Protease Inhibitors - administration & dosage; HIV Protease Inhibitors - therapeutic use; Humans; Male; Middle Aged; Outpatients; Retrospective Studies; Ritonavir - administration & dosage; Ritonavir - therapeutic use; Treatment Outcome; Viral Load; Viremia - drug therapy

Low dose-ritonavir boosted protease inhibitors are increasingly being used for the first-line antiretroviral treatment, though their virological efficacy has just poorly been compared to alternative antiretroviral therapies. Here, we retrospectively investigated the virological responses of 316 prot...