Overexpression of VEGF165b, an Inhibitory Splice Variant of Vascular Endothelial Growth Factor, Leads to Insufficient Angiogenesis in Patients With Systemic Sclerosis - Manetti, Mirko; Guiducci, Serena; Romano, Eloisa; Ceccarelli, Claudia; Bellando-Randone, Silvia; Conforti, Maria Letizia; Ibba-Manneschi, Lidia; Matucci-Cerinic, Marco (Circulation research, 2011)
Keywords: Alternative Splicing - physiology; Cells, Cultured; Culture Media, Conditioned - pharmacology; Dermis - blood supply; Endothelial Cells - cytology; Endothelial Cells - physiology; Gene Expression - drug effects; Gene Expression - physiology; Humans; Ischemia - genetics; Ischemia - metabolism; Ischemia - physiopathology; Neovascularization, Pathologic - genetics; Neovascularization, Pathologic - metabolism; Neovascularization, Pathologic - physiopathology; Nuclear Proteins - genetics; Nuclear Proteins - metabolism; Phosphoproteins - genetics; Phosphoproteins - metabolism; Phosphorylation - drug effects; Phosphorylation - physiology; RNA-Binding Proteins; Scleroderma, Systemic - genetics; Scleroderma, Systemic - metabolism; Scleroderma, Systemic - physiopathology; Serine-Arginine Splicing Factors; Signal Transduction - drug effects; Signal Transduction - physiology; Transforming Growth Factor beta1 - genetics; Transforming Growth Factor beta1 - metabolism; Transforming Growth Factor beta1 - pharmacology; Vascular Endothelial Growth Factor A - genetics; Vascular Endothelial Growth Factor A - metabolism; Vascular Endothelial Growth Factor A - pharmacology; Vascular Endothelial Growth Factor B - genetics; Vascular Endothelial Growth Factor B - metabolism; Vascular Endothelial Growth Factor B - pharmacology; Vascular Endothelial Growth Factor Receptor-2 - metabolism