Modality-independent decoding of semantic information from the human brain

• Published in: Cerebral cortex (New York, N.Y. 1991) Vol. 24; no. 2; pp. 426 - 434
• Main Authors: Simanova, Irina, Hagoort, Peter, Oostenveld, Robert, van Gerven, Marcel A J
• Format: Journal Article
• Language: English
• Published: United States 01.02.2014
• Subjects: Adolescent; Adult; Auditory Perception - physiology; Brain - physiology; Brain Mapping - methods; Female; Humans; Imagination - physiology; Judgment - physiology; Magnetic Resonance Imaging; Male; Mental Recall - physiology; Names; Reading; Semantics; Signal Processing, Computer-Assisted; Speech Perception - physiology; Support Vector Machine; Visual Perception - physiology; Young Adult; searchlight; multivoxel pattern analysis; semantics; amodal; FMRI
• DOI: 10.1093/cercor/bhs324
• ISSN: 1460-2199; 1047-3211

An ability to decode semantic information from fMRI spatial patterns has been demonstrated in previous studies mostly for 1 specific input modality. In this study, we aimed to decode semantic category independent of the modality in which an object was presented. Using a searchlight method, we were able to predict the stimulus category from the data while participants performed a semantic categorization task with 4 stimulus modalities (spoken and written names, photographs, and natural sounds). Significant classification performance was achieved in all 4 modalities. Modality-independent decoding was implemented by training and testing the searchlight method across modalities. This allowed the localization of those brain regions, which correctly discriminated between the categories, independent of stimulus modality. The analysis revealed large clusters of voxels in the left inferior temporal cortex and in frontal regions. These voxels also allowed category discrimination in a free recall session where subjects recalled the objects in the absence of external stimuli. The results show that semantic information can be decoded from the fMRI signal independently of the input modality and have clear implications for understanding the functional mechanisms of semantic memory.