Effect of aspirin and acid on human jejunal mucosa. An ultrastructural study

• Published in: Gastroenterology (New York, N.Y. 1943) Vol. 76; no. 1; p. 50
• Main Authors: Ivey, K J, Baskin, W N, Krause, W J, Terry, B
• Format: Journal Article
• Language: English
• Published: United States 01.01.1979
• Subjects: Administration, Oral; Aspirin - administration & dosage; Aspirin - toxicity; Humans; Hydrochloric Acid - administration & dosage; Hydrochloric Acid - toxicity; Intestinal Diseases - chemically induced; Intestinal Diseases - pathology; Intestinal Mucosa - drug effects; Intestinal Mucosa - pathology; Intestinal Mucosa - ultrastructure; Intestine, Small - drug effects; Intestine, Small - pathology; Intestine, Small - ultrastructure; Suspensions

To determine the effects of aspirin and hydrochloric acid on human jejunal mucosa, three obese patients with a small intestinal bypass that opened on the abdominal wall as a mucous fistula were studied. An 80-mM solution of HCl, a 40-mM suspension of aspirin (equivalent to two tablets in a glass of...