Accumulation or production of arsenobetaine in humans?

• Published in: Journal of environmental monitoring Vol. 12; no. 4; pp. 832 - 837
• Main Authors: Newcombe, Chris, Raab, Andrea, Williams, Paul N, Deacon, Claire, Haris, Parvez I, Meharg, Andrew A, Feldmann, Jörg
• Format: Journal Article
• Language: English
• Published: England 01.04.2010
• Subjects: Adult; Arsenicals - analysis; Arsenicals - metabolism; Arsenicals - urine; Diet; Humans; Male; Middle Aged; Oryza - chemistry; Quality Control

Arsenobetaine has always been referred to as a non-toxic but readily bioavailable compound and the available data would suggest that it is neither metabolised by nor accumulated in humans. Here this study investigates the urine of five volunteers on an arsenobetaine exclusive diet for twelve days an...