HDL (High-Density Lipoprotein) Cholesterol Efflux Capacity Is Associated With Incident Cardiovascular Disease in the General Population

• Published in: Arteriosclerosis, thrombosis, and vascular biology Vol. 39; no. 9; p. 1874
• Main Authors: Ebtehaj, Sanam, Gruppen, Eke G, Bakker, Stephan J L, Dullaart, Robin P F, Tietge, Uwe J F
• Format: Journal Article
• Language: English
• Published: United States 01.09.2019
• Subjects: Adult; Aged; C-Reactive Protein - analysis; Cardiovascular Diseases - etiology; Cardiovascular Diseases - metabolism; Cholesterol, HDL - metabolism; Female; Humans; Male; Middle Aged; Prospective Studies; atherosclerosis; foam cells; cardiovascular disease; biomarker; urinary albumin excretion; albumins

Focus is shifting from HDL-C (high-density lipoprotein cholesterol) as predictive biomarker for cardiovascular disease (CVD) towards antiatherogenic HDL functionalities. Still, limited data exist on the prospective association of HDL function metrics with CVD events. The current work aimed to determ...