The strengths and weaknesses of NMR spectroscopy and mass spectrometry with particular focus on metabolomics research

• Published in: Methods in molecular biology (Clifton, N.J.) Vol. 1277; p. 161
• Main Author: Emwas, Abdul-Hamid M
• Format: Journal Article
• Language: English
• Published: United States 2015
• Subjects: Animals; Carbon-13 Magnetic Resonance Spectroscopy; Chromatography, Liquid; Gas Chromatography-Mass Spectrometry; Humans; Magnetic Resonance Spectroscopy - methods; Mass Spectrometry - methods; Metabolomics - methods; Proton Magnetic Resonance Spectroscopy

Mass spectrometry (MS) and nuclear magnetic resonance (NMR) have evolved as the most common techniques in metabolomics studies, and each brings its own advantages and limitations. Unlike MS spectrometry, NMR spectroscopy is quantitative and does not require extra steps for sample preparation, such a...