Trandolapril restores circadian blood pressure variation in normoalbuminuric normotensive Type 1 diabetic patients

• Published in: Journal of diabetes and its complications Vol. 15; no. 2; pp. 75 - 79
• Main Authors: CZUPRYNIAK, Leszek, WISNIEWSKA-JAROSINSKA, Maria, DRZEWOSKI, Jozef
• Format: Journal Article
• Language: English
• Published: New York, NY Elsevier Science 01.03.2001
• Subjects: Adult; Albuminuria; Antihypertensive agents; Antihypertensive Agents - therapeutic use; Biological and medical sciences; Blood Pressure - drug effects; Blood Pressure Monitoring, Ambulatory; Cardiovascular system; Circadian Rhythm; Diabetes Mellitus, Type 1 - drug therapy; Diabetes Mellitus, Type 1 - physiopathology; Diastole - drug effects; Female; Humans; Indoles - therapeutic use; Male; Medical sciences; Pharmacology. Drug treatments; Systole - drug effects; Endocrinopathy; Human; Immunopathology; Treatment efficiency; Autoimmune disease; Circadian rhythm; Trandolapril; Chemotherapy; Treatment; Insulin dependent diabetes; Adult; Blood pressure; ACE inhibitor

A large proportion, from 30% to 50%, of diabetic patients frequently manifests loss of the normal diurnal variation of blood pressure, i.e. their blood pressure does not show at least 10% fall at night (non-dippers). It has been demonstrated that non-dippers are at increased risk of end-organ damage...