Genetic Deletion of p90 Ribosomal S6 Kinase 2 Alters Patterns of 5-Hydroxytryptamine2A Serotonin Receptor Functional Selectivity

The concept of functional selectivity has now thoroughly supplanted the previously entrenched notion of intrinsic efficacy by explaining how agonists and antagonists exhibit a range of efficacies for distinct receptor-mediated responses. It is noteworthy that functional selectivity accommodates sign...

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Bibliographic Details
Published inMolecular pharmacology Vol. 77; no. 3; pp. 327 - 338
Main Authors Strachan, Ryan T., Sciaky, Noah, Cronan, Mark R., Kroeze, Wesley K., Roth, Bryan L.
Format Journal Article
LanguageEnglish
Published The American Society for Pharmacology and Experimental Therapeutics 01.03.2010
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