A FEMALE CASE OF SPINOCEREBELLAR ATAXIA TYPE 10 WITH SUICIDAL BEHAVIOR AND ENDOCRINPATHIES ASSOCIATED WITH A MASSIVE EXPANSION (ATTCT) OF THE GENE ATXN10

• Published in: Actas espanolas de psiquiatria Vol. 50; no. 1; pp. 58 - 62
• Main Authors: Ramirez-Garcia, Sergio A, Sánchez-Corona, José, Volpini-Bertran, Víctor, Moran-Moguel, María Cristina, Gutiérrez-Rubio, Susan A, Castañeda-Cisneros, Gema, Jiménez-Gil, Javier, Garcia-Cruz, Diana
• Format: Journal Article
• Language: English
• Published: Spain Actas Españolas de Psiquiatría 01.01.2022
• Subjects: Ataxin-10; DNA Repeat Expansion; Female; Humans; Letter to Editor; Mexico; Spinocerebellar Ataxias - genetics; Suicidal Ideation; Mexico

Spinocerebellar ataxia type 10 (SCA10) is characteri- zed by ataxia, psychiatric disorders convulsions, and locus at 22q13.311. It is caused by expansions between 800-4500 pentanucleotide ATTCT repeats in intron 9 of the ATXN10 gene1-2. The ATXN10 gene encodes ataxin-10 protein (known as E46L) invol...