Spatial analysis of magnetic resonance T1ρ and T2 relaxation times improves classification between subjects with and without osteoarthritis

• Published in: Medical physics (Lancaster) Vol. 36; no. 9Part1; pp. 4059 - 4067
• Main Authors: Carballido‐Gamio, Julio, Stahl, Robert, Blumenkrantz, Gabrielle, Romero, Adan, Majumdar, Sharmila, Link, Thomas M.
• Format: Journal Article
• Language: English
• Published: American Association of Physicists in Medicine 01.09.2009
• Subjects: biomedical MRI; bone; Diseases; Entropy; Image registration; image texture; laminar; Magnetic resonance; Magnetic resonance imaging; magnetic resonance imaging (MRI); Magnetic Resonance Physics; medical image processing; Medical imaging; Medical magnetic resonance imaging; orthopaedics; osteoarthritis (OA); Probability theory, stochastic processes, and statistics; Relaxation times; sensitivity analysis; Sequence analysis; Spatial analysis; statistical analysis; T1ρ; texture

Purpose: Studies have shown that functional analysis of knee cartilage based on magnetic resonance (MR) relaxation times is a valuable tool in the understanding of osteoarthritis (OA). In this work, the regional spatial distribution of knee cartilageT1ρ and T2 relaxation times based on texture and l...