Cancer chemoprevention by cyclooxygenase 2 (COX-2) blockade: results of case control studies

• Published in: Sub-cellular biochemistry Vol. 42; p. 193
• Main Authors: Harris, Randall E, Beebe-Donk, Joanne, Alshafie, Galal A
• Format: Journal Article
• Language: English
• Published: United States 2007
• Subjects: Arthritis - drug therapy; Case-Control Studies; Cyclooxygenase 2 Inhibitors - therapeutic use; Humans; Logistic Models; Multicenter Studies as Topic; Neoplasms - drug therapy; Neoplasms - genetics; Neoplasms - pathology; Neoplasms - prevention & control; Odds Ratio; Organ Specificity - drug effects; Organ Specificity - genetics; Risk Factors; Sex Factors; Tumor Burden - drug effects; Tumor Burden - genetics

Significant use of selective cyclooxygenase-2 (COX-2) blocking agents prescribed for the treatment of arthritis during 1999 to 2005 facilitates epidemiologic investigations to illuminate their chemopreventive effects against human cancer. We therefore conducted a set of case control studies of selec...