妊娠合并系统性红斑狼疮患者子代远期发育结局的研究进展
系统性红斑狼疮(systemic lupus erythematosus,SLE)是一种累及多器官多系统的自身免疫性结缔组织病,好发于女性育龄期.与一般人群相比,妊娠合并SLE患者发生早产、宫内生长受限等不良围生期结局的风险明显增加.另外,SLE患者的子代在宫内暴露于母体自身抗体、细胞因子和药物等,也可能对子代的远期发育造成不利影响.该文从血液系统、循环系统、神经系统、免疫系统等方面对妊娠合并SLE患者子代的远期发育结局予以总结....
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| Published in | Zhongguo dang dai er ke za zhi Vol. 25; no. 4; pp. 415 - 419 |
|---|---|
| Main Authors | , |
| Format | Journal Article |
| Language | Chinese English |
| Published |
湖南省长沙市湘雅路87号 中南大学湘雅医院内
北京大学人民医院儿科,北京 100044
15.04.2023
《中国当代儿科杂志》编辑部 |
| Subjects | |
| Online Access | Get full text |
| ISSN | 1008-8830 2096-9228 |
| DOI | 10.7499/j.issn.1008-8830.2211036 |
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| Abstract | 系统性红斑狼疮(systemic lupus erythematosus,SLE)是一种累及多器官多系统的自身免疫性结缔组织病,好发于女性育龄期.与一般人群相比,妊娠合并SLE患者发生早产、宫内生长受限等不良围生期结局的风险明显增加.另外,SLE患者的子代在宫内暴露于母体自身抗体、细胞因子和药物等,也可能对子代的远期发育造成不利影响.该文从血液系统、循环系统、神经系统、免疫系统等方面对妊娠合并SLE患者子代的远期发育结局予以总结. |
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| AbstractList | 系统性红斑狼疮(systemic lupus erythematosus,SLE)是一种累及多器官多系统的自身免疫性结缔组织病,好发于女性育龄期.与一般人群相比,妊娠合并SLE患者发生早产、宫内生长受限等不良围生期结局的风险明显增加.另外,SLE患者的子代在宫内暴露于母体自身抗体、细胞因子和药物等,也可能对子代的远期发育造成不利影响.该文从血液系统、循环系统、神经系统、免疫系统等方面对妊娠合并SLE患者子代的远期发育结局予以总结. 系统性红斑狼疮（systemic lupus erythematosus，SLE）是一种累及多器官多系统的自身免疫性结缔组织病，好发于女性育龄期。与一般人群相比，妊娠合并SLE患者发生早产、宫内生长受限等不良围生期结局的风险明显增加。另外，SLE患者的子代在宫内暴露于母体自身抗体、细胞因子和药物等，也可能对子代的远期发育造成不利影响。该文从血液系统、循环系统、神经系统、免疫系统等方面对妊娠合并SLE患者子代的远期发育结局予以总结。 |
| Author | 张懿敏 邵树铭 |
| AuthorAffiliation | 北京大学人民医院儿科,北京 100044 |
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| Author_FL | ZHANG Yi-Min SHAO Shu-Ming |
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| Copyright | Copyright © Wanfang Data Co. Ltd. All Rights Reserved. 2023 《中国当代儿科杂志》编辑部 Contemporary Chinese journal pediatrics |
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| DocumentTitle_FL | Research progress on long-term developmental outcomes of offspring of pregnant women with systemic lupus erythematosus |
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| Keywords | 子代 系统性红斑狼疮 妊娠 远期结局 |
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| Title | 妊娠合并系统性红斑狼疮患者子代远期发育结局的研究进展 |
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