T1 relaxation times for viability evaluation of the engrafted and the native liver in a rat model of heterotopic auxiliary liver transplantation: a pilot study

• Published in: NMR in biomedicine Vol. 14; no. 6; pp. 350 - 359
• Main Authors: FAN, Ye-Dong, VANZIELEGHEM, Bart, ACHTEN, Eric, DE DEENE, Yves, DEFREYNE, Luc, PRAET, Marleen, VAN HUYSSE, Jacques, KUNNEN, Marc, DE HEMPTINNE, Bernard
• Format: Journal Article
• Language: English
• Published: Chichester Wiley 01.10.2001
• Subjects: Alanine Transaminase - blood; Animals; Atrophy; Biological and medical sciences; Common Bile Duct - surgery; Digestive system; Gastroenterology. Liver. Pancreas. Abdomen; Graft Survival; Hepatectomy; Investigative techniques, diagnostic techniques (general aspects); Ligation; Liver - pathology; Liver - physiology; Liver Transplantation; Liver. Biliary tract. Portal circulation. Exocrine pancreas; Magnetic Resonance Imaging; Male; Medical sciences; Models, Animal; Other diseases. Semiology; Pilot Projects; Postoperative Complications; Radiodiagnosis. Nmr imagery. Nmr spectrometry; Rats; Rats, Wistar; Time Factors; Transplantation, Heterotopic; Postoperative; Evaluation; Graft(material); Animal model; Rat; Liver; Intensity; Rodentia; Hepatic disease; Experimental study; Nuclear magnetic resonance imaging; Relaxation time; Vertebrata; Mammalia; Animal; Digestive diseases; Signal analysis; Heterotopic transplantation; Viability

Following a heterotopic auxiliary liver transplantation, commonly used measurements are either invasive or non-indicative of individual viability of the coexisting engrafted and native livers. Magnetic resonance imaging (MRI) was therefore tested for its potential to monitor the post-transplant hepa...