Anionic gels as vehicles for electrically-modulated drug delivery. I. Solvent and drug transport phenomena

• Published in: Pharmaceutical research Vol. 13; no. 12; p. 1865
• Main Authors: Hsu, C S, Block, L H
• Format: Journal Article
• Language: English
• Published: United States 01.12.1996
• Subjects: Acrylic Resins - chemistry; Drug Carriers; Electricity; Gels - chemistry; Hydrocortisone - analysis; Polysaccharides, Bacterial - chemistry; Sepharose - chemistry

The purpose of this study was to elucidate the in vitro behavior of anionic gels as formulation matrices for electrically-modulated drug delivery. Agarose and combinations of agarose with other anionic polymers (carbomer 934P; xanthan gum) were selected and tested to evaluate their potential for dru...