Poikiloderma, alopecia, retrognathism and cleft palate: the PARC syndrome. Is this an undescribed dominantly inherited syndrome?

• Published in: Dermatologica Vol. 181; no. 2; p. 142
• Main Authors: Verloes, A, Soyeur-Broux, M, Arrese-Estrada, J, Piérard-Franchimont, C, Dodinval, P, Piérard, G E
• Format: Journal Article
• Language: English
• Published: Switzerland 1990
• Subjects: Alopecia - genetics; Alopecia - pathology; Cleft Palate - genetics; Cleft Palate - pathology; Hair - pathology; Humans; Infant, Newborn; Male; Retrognathia - genetics; Retrognathia - pathology; Rothmund-Thomson Syndrome - genetics; Rothmund-Thomson Syndrome - pathology; Skin - pathology; Syndrome

We report a clinicopathological observation concerning a man and his son affected by the same disease. The main cutaneous lesions included poikiloderma congenitale and generalized alopecia respecting the pubic area. These anomalies were associated with cleft palate and Robin sequence in the boy. The...