Congestive cardiomyopathy and spasm of coronary microvascularisation in man. Electron microscopic evidence
This paper reports our observations of right ventricular biopsies taken from a 23 year old patient with a congestive cardiomyopathy. The ultrastructural examination of these samples revealed coronary capillary and arteriolar spasms, as well as an ischemic aspect of the myocytes. The responsibility o...
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Published in | Annales de pathologie Vol. 7; no. 3; p. 223 |
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Main Authors | , , , , |
Format | Journal Article |
Language | English |
Published |
France
1987
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Abstract | This paper reports our observations of right ventricular biopsies taken from a 23 year old patient with a congestive cardiomyopathy. The ultrastructural examination of these samples revealed coronary capillary and arteriolar spasms, as well as an ischemic aspect of the myocytes. The responsibility of the coronary microcirculation in the genesis of dilated cardiomyopathies has been suspected for a long time. It has recently been demonstrated in the Syrian hamster, but it has never been clearly evidenced in man. The case that we present seems to confirm this hypothesis. The fact that the spasm is a transitory phenomenon and that it most probably does not involve all areas of the myocardium simultaneously could explain the difficulty encountered in observing this phenomenon in endomyocardial biopsies. |
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AbstractList | This paper reports our observations of right ventricular biopsies taken from a 23 year old patient with a congestive cardiomyopathy. The ultrastructural examination of these samples revealed coronary capillary and arteriolar spasms, as well as an ischemic aspect of the myocytes. The responsibility of the coronary microcirculation in the genesis of dilated cardiomyopathies has been suspected for a long time. It has recently been demonstrated in the Syrian hamster, but it has never been clearly evidenced in man. The case that we present seems to confirm this hypothesis. The fact that the spasm is a transitory phenomenon and that it most probably does not involve all areas of the myocardium simultaneously could explain the difficulty encountered in observing this phenomenon in endomyocardial biopsies. |
Author | Pfister, A Lucet, P Duboc, D Da Lage, C Toussaint, M |
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BackLink | https://www.ncbi.nlm.nih.gov/pubmed/3435613$$D View this record in MEDLINE/PubMed |
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Snippet | This paper reports our observations of right ventricular biopsies taken from a 23 year old patient with a congestive cardiomyopathy. The ultrastructural... |
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SubjectTerms | Adult Cardiomyopathy, Dilated - etiology Cardiomyopathy, Dilated - pathology Coronary Vasospasm - complications Coronary Vasospasm - pathology Humans Male Microscopy, Electron Myocardium - pathology Myocardium - ultrastructure |
Title | Congestive cardiomyopathy and spasm of coronary microvascularisation in man. Electron microscopic evidence |
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