Quantitative DNA determination by image analysis. II. Application to human and canine pulmonary cytology

• Published in: Analytical and quantitative cytology Vol. 5; no. 4; p. 263
• Main Authors: Pak, H Y, Teplitz, R L, Ashdjian, V, Yokota, S B, Hammond, W G, Benfield, J R
• Format: Journal Article
• Language: English
• Published: United States 01.12.1983
• Subjects: Adenocarcinoma - analysis; Animals; Carcinoma, Bronchogenic - analysis; Carcinoma, Small Cell - analysis; Carcinoma, Squamous Cell - analysis; DNA - analysis; DNA, Neoplasm - analysis; Dogs; Humans; Image Enhancement - methods; Lung - analysis; Lung - pathology; Lung Neoplasms - analysis; Metaplasia - pathology

Comparative DNA measurements in human and canine preneoplastic and neoplastic tracheobronchial cells were made with the application of computerized image analysis. Canine studies demonstrated that the sequence of cellular events that precede epidermoid lung cancer simulates precisely the progression...