Isolation of Haemophilus somnus antigens and their use as vaccines for prevention of bovine thromboembolic meningoencephalitis

• Published in: American journal of veterinary research Vol. 45; no. 2; p. 234
• Main Authors: Stephens, L R, Little, P B, Wilkie, B N, Barnum, D A
• Format: Journal Article
• Language: English
• Published: United States 01.02.1984
• Subjects: Animals; Antibodies, Bacterial - analysis; Antigens, Bacterial - isolation & purification; Bacterial Vaccines - immunology; Bacterial Vaccines - isolation & purification; Cattle; Cattle Diseases - immunology; Cattle Diseases - prevention & control; Chromatography, Ion Exchange - methods; Haemophilus - immunology; Meningitis, Haemophilus - immunology; Meningitis, Haemophilus - prevention & control; Meningitis, Haemophilus - veterinary; Meningoencephalitis - immunology; Meningoencephalitis - prevention & control; Meningoencephalitis - veterinary; Vaccination - veterinary

Antigens extracted from Haemophilus somnus were examined for their suitability as vaccines for prevention of thromboembolic meningoencephalitis and as antigens in immunologic tests for detection of susceptible cattle. Saline extraction of whole H somnus cells produced an outer membrane complex (OMC)...