An oral SARS-CoV-2 Mpro inhibitor clinical candidate for the treatment of COVID-19 - Owen, Dafydd R; Allerton, Charlotte M N; Anderson, Annaliesa S; Aschenbrenner, Lisa; Avery, Melissa; Berritt, Simon; Boras, Britton; Cardin, Rhonda D; Carlo, Anthony; Coffman, Karen J; Dantonio, Alyssa; Li, Di; et al. (Science (American Association for the Advancement of Science), 2021)
Keywords: Antiviral activity; Antiviral agents; Antiviral drugs; Bioavailability; Clinical trials; Coronaviruses; COVID-19; COVID-19 vaccines; DNA-directed RNA polymerase; Drug development; Health services; Literary Devices; Oral administration; Pandemics; Polyproteins; Protease; Protease inhibitors; Proteinase inhibitors; Respiratory diseases; RNA polymerase; RNA-directed RNA polymerase; Safety; Selectivity; Severe acute respiratory syndrome coronavirus 2; Vaccines; Viral diseases